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A 2025 matched-cohort study found men who started testosterone therapy had significantly higher rates of tendon tears and repairs at one and two years compared to controls, a pattern the authors attributed to testosterone's effect on tendon biomechanics outpacing the tissue's regenerative capacity Sherman et al

The Bottom Line Taken together, the Swedish and Japanese studies, along with decades of broader research, support a reassuring conclusion: there is no credible causal evidence linking typical acetaminophen use during pregnancy to autism, ADHD, or other neurodevelopmental disorders

REM) sleep (257, 258), but whether or not the effects of PregS on memory function in subjects with neuropsychiatric disorders and age-related neurodegenerative disease are mediated by enhancement of REM and/or non-REM sleep has not been fully elucidated (259, 260)

McKee's Pathology of the Skin